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Related Concept Videos

Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...

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Minimum Volume Vitrification of Immature Feline Oocytes
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Published on: June 24, 2020

Feline calicivirus strains isolated in Italy.

D Rinaldo1, M Foti, T Bottari

  • 1Department of Veterinary Public Health, School of Veterinary Medicine, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, Italy. donatellarinaldo@yahoo.it

Polish Journal of Veterinary Sciences
|February 21, 2009
PubMed
Summary
This summary is machine-generated.

Feline Calicivirus (FCV) vaccination using the FCV-F9 serotype may be less effective than expected. Studies show a low antigenic correlation between the FCV-F9 vaccine and field strains circulating in Sicily.

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Area of Science:

  • Veterinary Virology
  • Feline Infectious Diseases

Background:

  • Feline Calicivirus (FCV) is a significant pathogen causing oral and respiratory disease in cats.
  • The FCV-F9 serotype has been used as a vaccine basis due to perceived high correlation with field strains.

Purpose of the Study:

  • To assess the antigenic correlation between the FCV-F9 vaccine strain and FCV field strains from Sicily.
  • To evaluate the vaccine's efficacy against locally prevalent FCV strains.

Main Methods:

  • In vitro neutralization assays were performed.
  • FCV field strains were isolated from cats in Sicily with clinical signs of calicivirus infection.

Main Results:

  • A low antigenic correlation was observed between the FCV-F9 vaccine strain and the isolated Sicilian FCV field strains.
  • This suggests limited cross-protection from the FCV-F9 vaccine against these local strains.

Conclusions:

  • The FCV-F9 vaccine may not provide adequate protection against FCV strains circulating in the feline population of Sicily.
  • Further research into broader-spectrum FCV vaccines or regionally specific vaccine strain selection is warranted.