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Feline calicivirus strains isolated in Italy
1Department of Veterinary Public Health, School of Veterinary Medicine, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, Italy. donatellarinaldo@yahoo.it
Polish Journal of Veterinary Sciences
|February 21, 2009
Summary
Feline Calicivirus (FCV) vaccination using the FCV-F9 serotype may be less effective than expected. Studies show a low antigenic correlation between the FCV-F9 vaccine and field strains circulating in Sicily.
Area of Science:
- Veterinary Virology
- Feline Infectious Diseases
Background:
- Feline Calicivirus (FCV) is a significant pathogen causing oral and respiratory disease in cats.
- The FCV-F9 serotype has been used as a vaccine basis due to perceived high correlation with field strains.
Purpose of the Study:
- To assess the antigenic correlation between the FCV-F9 vaccine strain and FCV field strains from Sicily.
- To evaluate the vaccine's efficacy against locally prevalent FCV strains.
Main Methods:
- In vitro neutralization assays were performed.
- FCV field strains were isolated from cats in Sicily with clinical signs of calicivirus infection.
Main Results:
- A low antigenic correlation was observed between the FCV-F9 vaccine strain and the isolated Sicilian FCV field strains.
- This suggests limited cross-protection from the FCV-F9 vaccine against these local strains.
Conclusions:
- The FCV-F9 vaccine may not provide adequate protection against FCV strains circulating in the feline population of Sicily.
- Further research into broader-spectrum FCV vaccines or regionally specific vaccine strain selection is warranted.
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