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Updated: Jun 25, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Case of bladder cancer following adjuvant external beam radiation for prostate cancer]
Kouhei Nishikawa1, Norihito Soga, Manabu Kato
1Department of Nephrourologic Surgery and Andrology, Mie University Graduate School of Medicine.
Abstract:
A 57-year-old male with a history of right renal cell carcinoma was diagnosed with prostate carcinoma associated with a high PSA level (5.2 ng/ml). Histological examination of the resected prostate specimen obtained by radical prostatectomy revealed well differentiated adenocarcinoma, Gleason score 3 + 3, and pT3aN0M0. After six months of observation, an elevation of PSA level was recognized and local recurrence was suspected. Therefore, radiotherapy with a total of 61.2 Gy was administered. Seventeen months later, bladder cancer was diagnosed. It had to be treated with pelvic evisceration because of suspicious heavy adhesions due to prior treatments. Histology findings were urothelial carcinoma in situ, G3, and pTisN0M0.

