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Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
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Published on: October 28, 2020

[Prognostic value of structural and functional changes in the left ventricle with respect to coronary heart diseases]

A N Shopin, Ia B Khovaeva

    Klinicheskaia Meditsina
    |February 21, 2009
    PubMed

    Insights

    Individuals at high risk for cardiovascular disease show detrimental left ventricular changes, including impaired function and structure. These alterations serve as negative prognostic indicators for coronary heart disease development.

    Area of Science:

    • Cardiology
    • Cardiovascular Medicine
    • Echocardiography

    Background:

    • Cardiovascular diseases (CVD) pose a significant global health burden.
    • Early identification of individuals at high risk is crucial for timely intervention.
    • Left ventricular (LV) structural and functional changes can precede overt CVD events.

    Purpose of the Study:

    • To investigate LV structural and functional alterations in high-risk subjects.
    • To evaluate the prognostic significance of these changes for coronary heart disease (CHD).

    Main Methods:

    • Isometric stress Doppler echocardiography.
    • 24-hour Holter monitoring.
    • Veloergometry (exercise testing).

    Main Results:

    • High-risk subjects exhibited increased LV myocardial mass, thinned ventricular walls, and dilated/spherized LV cavity.
    • Impaired LV contractility and relaxation were observed in the high-risk group.
    • Walk tests indicated asynergic LV areas, reduced ejection fraction, and diastolic dysfunction.

    Conclusions:

    • Significant structural and functional LV remodeling occurs in individuals at high cardiovascular risk.
    • These echocardiographic and functional abnormalities are negative prognostic factors for developing coronary heart disease.

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