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Updated: Jun 25, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
[Surgical treatment of mitral valve endocarditis]
1Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Japan.
Abstract:
Mitral valve repair is considered to be the procedure of choice for any type of mitral regurgitation, including infective endocarditis, in terms of left ventricular function and event-free survival. We reviewed 120 consecutive patients who underwent mitral valve repair for active or healed endocarditis between 1991 and 2008. The repair rate for patients with infective endocarditis was 90% during the same period. The patients comprised 72 men and 48 women whose mean age was 48 +/- 17 years. Of the 120 patients, 40 underwent mitral valve repair during the active phase of infective endocarditis. The repair procedures included patch grafting using glutaraldehyde-treated autologous pericardium in 39 patients and chordal reconstruction using expanded polytetrafluoroethylene (ePTFE) in 57 patients which were combined with a prosthetic ring in 82 patients. The 10-year survival rates including hospital death and freedom from reoperation were 92 +/- 4% and 96 +/- 2%, respectively. Mitral valve repair for active or healed endocarditis can be performed with low operative mortality rates. Complex mitral valve repair using autologous pericardium and/or ePTFE for neochordae expands the possibility of repair, is durable, and is associated with excellent long-term results.
Insights
Mitral valve repair is a preferred treatment for mitral regurgitation, even with infective endocarditis. This study shows durable, excellent long-term results and survival rates for patients undergoing complex mitral valve repair.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Biomaterials Science
Context:
- Mitral valve regurgitation (MVR) necessitates timely intervention for optimal patient outcomes.
- Infective endocarditis (IE) poses unique challenges to mitral valve integrity and surgical repair.
- Mitral valve repair (MVR) is increasingly favored over replacement for MVR due to better preservation of left ventricular function.
Purpose:
- To evaluate the long-term efficacy and safety of mitral valve repair in patients with active or healed infective endocarditis.
- To assess the feasibility and outcomes of complex mitral valve repair techniques using autologous pericardium and expanded polytetrafluoroethylene (ePTFE).
Summary:
- A review of 120 patients (72 men, 48 women; mean age 48 years) undergoing mitral valve repair for IE between 1991 and 2008.
- Repair techniques included patch grafting with autologous pericardium and chordal reconstruction with ePTFE, often combined with a prosthetic ring.
- The 10-year survival rate was 92% and freedom from reoperation was 96%, demonstrating the durability and success of these repair methods.
Impact:
- Mitral valve repair for IE can be achieved with low operative mortality and excellent long-term results.
- Advanced repair techniques using pericardium and ePTFE expand the applicability of mitral valve repair in complex IE cases.
- This approach offers a durable solution, improving event-free survival and preserving left ventricular function in patients with IE-related mitral valve disease.
Related Concept Videos
Mitral Stenosis III: Medical Management
Endocarditis III: Medical Management
Mitral Regurgitation III: Medical Management
Mitral Valve Prolapse II: Assessment and Management
Mitral Stenosis I: Introduction
Mitral Stenosis IV: Nursing Management

