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Intestinal intussusception due to a pyogenic granuloma
Zorica Stojsic1, Dimitrije Brasanac, George Kokai
1Institute of Pathology, University of Belgrade, Serbia.
The Turkish Journal of Pediatrics
|February 21, 2009
Summary
Pyogenic granuloma (PG), a rare gastrointestinal vascular tumor, can cause intestinal obstruction in children. This case highlights ileal PG in a 13-year-old girl, emphasizing its consideration in pediatric gastrointestinal polypoid lesions.
Area of Science:
- Gastroenterology
- Pediatric Surgery
- Surgical Pathology
Background:
- Pyogenic granuloma (PG), or lobular capillary hemangioma, is a benign vascular tumor typically found on skin and oral mucosa.
- Gastrointestinal (GI) PGs are rare, making their diagnosis challenging.
Observation:
- A 13-year-old girl presented with intestinal obstruction.
- Ileal pyogenic granuloma was diagnosed, involving the full thickness of the intestinal wall.
- Histopathology confirmed a vascular proliferation with intravascular components.
Findings:
- Immunohistochemistry revealed positivity for CD31, CD34, and von Willebrand factor.
- Staining for glucose transporter-1 protein (GLUT1) and human herpes virus 8 (HHV-8) was negative.
- These findings are consistent with pyogenic granuloma.
Implications:
- Pyogenic granuloma should be included in the differential diagnosis of pediatric gastrointestinal polypoid lesions.
- Early consideration can aid in timely diagnosis and management of obstructive GI symptoms in children.
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