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Related Experiment Video

Updated: Jun 25, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
10:22

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure

Published on: February 12, 2018

Development of a dynamic test phantom for optical topography.

Peck H Koh1, Clare E Elwell, David T Delpy

  • 1Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, United Kingdom. pkoh@medphys.ucl.ac.uk

Advances in Experimental Medicine and Biology
|February 21, 2009
PubMed
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We developed a novel dynamic tissue phantom for optical topography (OT) system calibration. This phantom accurately simulates real-time haemodynamic changes, improving OT system testing and development.

Area of Science:

  • Biomedical Optics
  • Medical Imaging Technology
  • Neuroscience Instrumentation

Background:

  • Optical topography (OT) is a near-infrared spectroscopy (NIRS) technique used for mapping haemodynamic and oxygenation changes.
  • Developing and calibrating OT systems requires realistic tissue-simulating phantoms capable of dynamic property changes.

Purpose of the Study:

  • To present a novel dynamic tissue phantom for controlled, spatially and temporally varying optical properties.
  • To enable realistic simulation of cerebral haemodynamic responses for OT system development and testing.

Main Methods:

  • A modified liquid crystal display (LCD) was integrated into a tissue-simulating epoxy resin phantom.
  • The LCD allows for flexible, rapid, and localized changes in optical attenuation across different phantom regions.

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Last Updated: Jun 25, 2026

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure
10:22

Fabrication and Characterization of Optical Tissue Phantoms Containing Macrostructure

Published on: February 12, 2018

A Stable Phantom Material for Optical and Acoustic Imaging
04:54

A Stable Phantom Material for Optical and Acoustic Imaging

Published on: June 16, 2023

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy
09:25

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Published on: August 22, 2018

Main Results:

  • The dynamic phantom successfully reproduced localized and time-varying attenuation changes.
  • Demonstrated the phantom's utility in simulating functional activation-associated haemodynamic responses.

Conclusions:

  • The novel dynamic tissue phantom offers a controlled method for testing and calibrating optical topography systems.
  • This phantom enhances the development of NIRS-based neuroimaging technologies by providing realistic physiological simulations.