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Activity-guided isolation of antioxidant principles from Limoniastrum feei (Girard) Batt
Mehdi Chaabi1, Noureddine Beghidja, Samir Benayache
1LC1 UMR-CNRS 7175, Biotechnologies, Biomolécules et Innovations Thérapeutiques, Faculté de Pharmacie de Strasbourg, 78 route du Rhin, 67401 Illkirch, France.
Abstract:
Bioguided fractionation of a leaves extract from Limoniastrum feei (Girard) Batt. (Plumbaginaceae) led to the isolation of seven polyphenolic constituents: gallic acid (1), myrciaphenone A (2), myricetin-3-O-beta-galactopyranoside (3-1), epigallocatechin gallate (3-2), myricetin 3-O-alpha-rhamnopyranoside (4), quercetin (5) and myricetin (6). Gallic acid was the most antioxidant compound in DPPH [(0.94 +/- 0.68) microg/mL] and FRAP [(0.83 +/- 0.15) microM Fe2+/mL] tests, whereas myricetin was a more specific superoxide radical scavenger since it was the most active product in the superoxide nitroblue tetrazolium hypoxanthine/xanthine oxidase test [(1.86 +/- 0.12) microg/mL].
