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Updated: Jun 25, 2026
09:38
A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
Published on: February 14, 2017
[Influencing hemostasis in substitute solution treatment]
Vnitrni Lekarstvi
|February 21, 2009
Summary
Fluid therapy can disrupt blood clotting in critically ill patients. Tromboelastography is an accurate method for monitoring these coagulation disturbances caused by artificial solutions.
Area of Science:
- Physiology
- Critical Care Medicine
Context:
- Critically ill patients face numerous stimuli impacting hemostasis.
- Fluid therapy is a common intervention with potential adverse effects on coagulation.
Purpose:
- To elucidate mechanisms impairing hemostatic balance during fluid therapy.
- To review the influence of artificial substitute solutions on coagulation.
- To highlight monitoring strategies for hemostatic disturbances.
Summary:
- All artificial fluid solutions possess the potential to disturb coagulation.
- The extent of coagulation disturbance depends on the solution's quantity, administration rate, and type.
- Tromboelastography offers superior accuracy for measuring coagulation disturbances compared to traditional methods.
Impact:
- Informs clinical practice regarding safe fluid administration in critical care.
- Guides the selection and monitoring of fluid therapies to mitigate coagulation risks.
- Enhances understanding of iatrogenic effects on hemostasis in hospitalized patients.
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