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Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment
Published on: December 27, 2024
What is your diagnosis? Lymph node cytology from a dog
Mark D Dunbar1, Heather L Wamsley
1Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA.
Veterinary Clinical Pathology
|February 21, 2009
Summary
A dog diagnosed with Lagenidium caninum infection showed characteristic hyphal sizes. Differentiating fungal agents relies on precise microscopic examination of hyphal diameter.
Area of Science:
- Veterinary Mycology
- Diagnostic Cytology
Background:
- Oomycete infections can cause significant morbidity in animals.
- Accurate identification of the causative agent is crucial for effective treatment.
Observation:
- A canine patient presented with severe swelling and draining tracts around the hock.
- Cytologic analysis revealed pyogranulomatous lymphadenitis with broad hyphae (11-22 microm).
Findings:
- The observed hyphal morphology was most consistent with Lagenidium caninum.
- Western blot analysis confirmed antibodies to Lagenidium sp. and ruled out Pythium insidiosum.
Implications:
- Hyphal diameter measurement in cytologic samples aids in differentiating Lagenidium caninum from similar oomycetes.
- This diagnostic approach can improve the accuracy of oomycete-related disease diagnosis in veterinary medicine.

