Related Experiment Video
Updated: Jun 25, 2026
09:37
Screening Foodstuffs for Class 1 Integrons and Gene Cassettes
Published on: June 19, 2015
INTEGRALL: a database and search engine for integrons, integrases and gene cassettes
Alexandra Moura1, Mário Soares, Carolina Pereira
1CESAM & Department of Biology, University of Aveiro, Campus Universitário de Santiago, Aveiro, Portugal. amoura@ua.pt
Bioinformatics (Oxford, England)
|February 21, 2009
Summary
INTEGRALL is a free database for organizing and accessing information on integrons. It provides over 4800 integron sequences, aiding researchers in studying their DNA, arrangements, and genetic contexts.
Area of Science:
- Genomics
- Bioinformatics
- Microbiology
Background:
- Integrons are genetic elements that play a crucial role in the dissemination of antibiotic resistance genes.
- Organizing and accessing information on integrons is essential for understanding their evolution and spread.
- Existing resources for integron data are fragmented and difficult to navigate.
Purpose of the Study:
- To develop a comprehensive, text-based search system for integron information.
- To create a public genetic repository for integron sequence data and nomenclature.
- To facilitate easy and interactive access to integron DNA sequences and their genetic contexts.
Main Methods:
- Development of a freely available, text-based search system named INTEGRALL.
- Curating and organizing over 4800 integron sequences into a single database.
- Implementing features for interactive access to sequence data, molecular arrangements, and genetic contexts.
Main Results:
- Release of INTEGRALL version 1.2, containing over 4800 integron sequences.
- Establishment of a public genetic repository for integron sequence data and nomenclature.
- Provision of scientists with an easy and interactive tool for exploring integron information.
Conclusions:
- INTEGRALL serves as a valuable resource for researchers studying integrons.
- The system enhances the accessibility and organization of critical genetic information.
- It supports advancements in understanding integron biology and their role in genetic element dynamics.
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