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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

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Related Experiment Video

Updated: Jun 25, 2026

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
08:59

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down

Published on: December 11, 2017

Targeted therapy: comprehensive review.

Ricardo Lima Barros Costa1

  • 1Western Pennsylvania Hospital, Pittsburgh, Pennsylvania. ricardocosta1@yahoo.com.br

The American Journal of Hospice & Palliative Care
|February 21, 2009
PubMed
Summary
This summary is machine-generated.

Cancer remains a leading diagnosis in hospice care. Targeted therapies, based on advances in cancer biology, offer significant clinical benefits and are changing cancer treatment standards.

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Area of Science:

  • Oncology
  • Palliative Care

Background:

  • Cancer is the most common primary diagnosis for hospice admissions.
  • Recent advances in understanding cancer biology have led to new therapeutic strategies.

Purpose of the Study:

  • To review cancer cell biology concepts.
  • To analyze the current use of targeted therapy in cancer care.
  • To highlight targeted therapy aspects relevant to hospice and palliative care professionals.

Main Methods:

  • Literature review of cancer cell biology.
  • Analysis of current targeted therapy standards of care.
  • Synthesis of data relevant to palliative care.

Main Results:

  • Targeted therapies, such as trastuzumab for HER2+ breast cancer, have shown significant survival benefits.
  • Targeted therapies are transforming the treatment landscape for various cancers.
  • Understanding cancer biology is key to developing effective targeted treatments.

Conclusions:

  • Targeted therapy represents a significant advancement in cancer treatment.
  • Hospice and palliative care professionals should be aware of targeted therapy's role in cancer care.
  • Continued research into cancer biology will likely yield further therapeutic innovations.