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Does androgen affect axonal transport of cholera toxin HRP in spinal motoneurons?
M Leslie1, N G Forger, S M Breedlove
1Psychology Department, University of California, Berkeley 94720.
Neuroscience Letters
|May 27, 1991
Abstract:
We examined the effect of systemic androgen levels upon the rate at which lumbosacral motoneurons are labeled with cholera toxin-conjugated horseradish peroxidase (CT-HRP) injected into target muscles. CT-HRP first reaches the spinal nucleus of the bulbocavernosus between 8 and 10 h after injection into the bulbocavernosus muscle of adult male rats, but the number of motoneurons filled with CT-HRP does not differ between androgen-treated and control castrates at any of the time points examined. Thus, contrary to current speculation, we found no evidence that androgen can affect retrograde transport of CT-HRP by rat motoneurons.