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Updated: Jun 25, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

Sinonasal lymphoma masquerading as persistent blepharoconjunctivitis.

Shailesh Gupta¹, Farhana Syed, Ravi K Murthy

¹Department of Ophthalmology, University of Florida College of Medicine, Jacksonville, Florida 32209, USA.

Orbit (Amsterdam, Netherlands)

|February 21, 2009

Summary

This summary is machine-generated.

Sinonasal lymphoma, a rare cancer of the nose and sinuses, can unusually present as persistent blepharoconjunctivitis. Chemotherapy effectively treated this rare presentation, leading to disease remission.

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Last Updated: Jun 25, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome

Published on: April 25, 2025

Area of Science:

Ophthalmology
Oncology
Pathology

Background:

Sinonasal lymphoma is a rare malignancy originating in the nasal cavity and paranasal sinuses.
Common symptoms include nasal obstruction, discharge, epistaxis, and facial swelling.
Orbital involvement can cause proptosis, blurred vision, and diplopia.

Observation:

This case report details an unusual ocular presentation of sinonasal lymphoma as persistent blepharoconjunctivitis.
The patient presented with symptoms primarily affecting the eye.
This presentation is atypical for sinonasal lymphoma.

Findings:

Biopsy of the tumor confirmed sinonasal lymphoma through positive immunoreactivity.
The diagnosis was established based on histopathological examination.
The specific subtype of lymphoma was identified via immunohistochemistry.

Implications:

Persistent blepharoconjunctivitis should be considered a potential, albeit rare, ocular symptom of sinonasal lymphoma.
Early diagnosis and appropriate treatment, such as chemotherapy, are crucial for successful management.
This case highlights the importance of a comprehensive diagnostic approach for unusual presentations of sinonasal malignancies.