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Updated: Jun 25, 2026

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
Published on: September 5, 2019
Spectroscopic tracking of molecular transport junctions generated by using click chemistry
Xiaodong Chen1, Adam B Braunschweig, Michael J Wiester
1Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA.
Abstract:
Click to fill the gap: The in situ modular fabrication of molecular transport junctions in nanogaps generated by on-wire lithography is achieved by using click chemistry (see picture). The formation of molecular junctions proceeds in high yields and can be used to test different molecules; the triazole group also maintains conjugation in the molecular wires. Raman spectroscopy is used to characterize the molecular assembly processes.

