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Related Concept Videos

Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

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Updated: Jun 25, 2026

Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food
08:38

Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food

Published on: May 6, 2013

Listeriosis.

Klara M Posfay-Barbe1, Ellen R Wald

  • 1Department of Pediatrics, Children's Hospital of Geneva, University Hospitals of Geneva, 6 rue Willy-Donzé, 1211 Geneva 14, Switzerland. Klara.PosfayBarbe@hcuge.ch

Seminars in Fetal & Neonatal Medicine
|February 24, 2009
PubMed
Summary
This summary is machine-generated.

Listeria monocytogenes causes foodborne illness, particularly in newborns. This bacterium invades cells and spreads, requiring specific antibiotic treatment for infected infants.

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Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
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Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes

Published on: May 27, 2015

Listeria monocytogenes Infection of the Brain
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Listeria monocytogenes Infection of the Brain

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Related Experiment Videos

Last Updated: Jun 25, 2026

Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food
08:38

Oral Transmission of Listeria monocytogenes in Mice via Ingestion of Contaminated Food

Published on: May 6, 2013

Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes
09:18

Assessing Bacterial Invasion of Cardiac Cells in Culture and Heart Colonization in Infected Mice Using Listeria monocytogenes

Published on: May 27, 2015

Listeria monocytogenes Infection of the Brain
05:02

Listeria monocytogenes Infection of the Brain

Published on: October 2, 2018

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Food Safety

Background:

  • Listeria monocytogenes is a Gram-positive bacterium responsible for significant foodborne illnesses.
  • It poses a particular risk to pregnant women and newborns, with a propensity for infecting the fetoplacental unit.
  • The pathogen contaminates various foods and can infect multiple animal species.

Purpose of the Study:

  • To detail the pathogenic mechanisms of Listeria monocytogenes.
  • To outline the virulence factors contributing to Listeria infection.
  • To describe the clinical presentation and treatment of neonatal Listeria infections.

Main Methods:

  • Review of literature on Listeria monocytogenes pathogenesis.
  • Analysis of virulence factors such as internalins and ActA.
  • Summary of host immune responses and clinical manifestations.
  • Compilation of current therapeutic guidelines.

Main Results:

  • Listeria monocytogenes invades host cells and utilizes cell-to-cell transmission for spread.
  • Key virulence factors include internalin A, internalin B, and ActA, regulated by positive regulatory factor A.
  • Neonatal infections present as early- or late-onset sepsis.

Conclusions:

  • Understanding Listeria's virulence factors is crucial for combating foodborne illness.
  • Prompt diagnosis and treatment, including ampicillin and gentamicin, are vital for neonatal outcomes.
  • Public health measures focusing on food safety are essential to prevent Listeria contamination.