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Updated: Jun 25, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
[Evaluation of endoscopic visualisation for identifying premalignant gastric lesions in a Columbian population using
Julio Alexander Díaz Pérez1, Carlos Alberto García Ramírez, Edgar Julián Ferreira Bohorquez
1Grupo de Investigación en Patología Estructural, Funcional y Clínica, Universidad Industrial de Santander, Bucaramanga, Colombia. pat_uis@yahoo.com
Aim:
To evaluate the performance of endoscopic visualization in the identification of premalignant gastric lesions, with histopathological examination of biopsy samples as a reference test, in Bucaramanga, Colombia.
Location:
League for the Fight Against Cancer, Bucaramanga, Colombia.
Design:
Diagnostic technology evaluation with cross-sectional sampling.
Measurements:
We calculate the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio (+), likelihood ratio (-), kappa index and the prevalence rate kappa.
Results:
A total of 155 patients were studied, with a mean age of 45.43 (14.15) years and an approximate male:female ratio of 2:1. The endoscopic visualization had a sensitivity of 87.84%, a specificity of 55.56%, a positive predictive value of 64.36%, a negative predictive value of 83.33%, a likelihood ratio+of 1.98, a likelihood ratio-de 0.22 and a kappa index of 0.4272, in the identification of preneoplastic lesions of the stomach in a population with a disease prevalence of 47.74%.
Conclusions:
The endoscopic visualization of the gastrointestinal mucosa, allows a moderate and fast identification of early preneoplastic lesions, providing an opportunity of its early histopathological diagnosis.
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