[Updates on severe traumatic brain injury management]
Related Experiment Video
Updated: Jun 25, 2026

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
Emilio Alted López1, Susana Bermejo Aznárez, Mario Chico Fernández
1UCI Trauma, Servicio de Medicina Intensiva, Hospital Universitario 12 de Octubre, Madrid, España. ealted.hdoc@salud.madrid.org
Abstract:
Traumatic brain injury (TBI) is an important reason of morbidity-mortality all over the world, affecting young males more and generating Public Health problem. Unfortunately, the advances in the pathophysiology knowledge have not followed a similar development in therapeutic options, there currently not being any contrasted neuroprotectants. In this article, we have reviewed the epidemiology, pathophysiology and therapeutic measures used in the management of patient with severe TBI. The general measures as well as those aimed at controlling intracranial hypertension, the role of the surgery and some more innovative therapeutic options currently under evaluation in these patients are analyzed.
