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Depressive symptoms in relation to physical functioning in pulmonary hypertension
Karl J Looper1, Andrena Pierre, David M Dunkley
1Department of Psychiatry, Sir Mortimer B. Davis - Jewish General Hospital, Montreal, Quebec, Canada H3T 1E2. karl.looper@mcgill.ca
Journal of Psychosomatic Research
|February 24, 2009
Summary
Depressive symptoms are linked to reduced physical functioning in patients with pulmonary hypertension (PH). Further research is needed to understand depression
Area of Science:
- Cardiology
- Psychiatry
Background:
- Pulmonary hypertension (PH) is a serious condition affecting lung and heart function.
- The impact of mental health, specifically depressive symptoms, on physical functioning in PH patients is not fully understood.
Purpose of the Study:
- To investigate the association between depressive symptoms and physical functioning in patients diagnosed with pulmonary hypertension (PH).
Main Methods:
- Fifty-two patients with precapillary or postcapillary PH completed self-report questionnaires assessing depressive symptoms and physical functioning.
- Hemodynamic variables were extracted from cardiac catheterization reports.
Main Results:
- Bivariate analysis revealed a significant association between physical functioning and depressive symptoms.
- Multivariate analysis indicated that depressive symptoms explained 9% of the variance in physical functioning, even after controlling for demographic and hemodynamic factors.
Conclusions:
- A significant association exists between depressive symptoms and diminished physical functioning in PH patients.
- These findings highlight the need for longitudinal studies to explore the potential impact of depression on PH disease outcomes.
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