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Related Experiment Video

Updated: Jun 25, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

Lateralized response timing deficits in autism.

Anna-Maria D'Cruz¹, Matthew W Mosconi, Shelly Steele

¹Center for Cognitive Medicine, University of Illinois at Chicago, Pittsburgh, Pennsylvania, USA.

Biological Psychiatry

|February 24, 2009

Summary

Individuals with autism show typical procedural learning but altered response timing. Specifically, they exhibit speeded rightward predictive saccades, indicating potential left hemisphere striatal dysfunction.

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Area of Science:

Neuroscience
Cognitive Psychology
Developmental Disorders

Background:

Procedural learning refines behavior through repetition, involving frontostriatal systems for motor response timing.
Frontostriatal disturbances are implicated in neurodevelopmental disorders like autism.

Purpose of the Study:

To investigate procedural learning and response timing in individuals with autism.
To explore potential frontostriatal system alterations in autism using an oculomotor task.

Main Methods:

Fifty-two individuals with autism and 54 controls performed serial reaction time and sensorimotor tasks.
Oculomotor responses (saccades) were analyzed for learning rate, precision, and timing.

Main Results:

Procedural learning and motor response precision were comparable between groups.
Individuals with autism demonstrated speeded rightward saccadic responses compared to controls.

Conclusions:

Autism is associated with unimpaired procedural learning but altered predictive response timing.
Speeded rightward saccades suggest atypical left hemisphere striatal chronometric function in autism.