Noninvasive imaging of atheromatous carotid plaques
Umar Sadat1, Zhi-Yong Li, Martin J Graves
1Department of Radiology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sadat.umar@gmail.com
Insights
Atherothrombosis, a disease of the arterial wall, leads to serious complications like stroke. Noninvasive imaging of carotid atheromatous plaques is crucial for understanding disease progression and guiding treatment.
Area of Science:
- Cardiovascular Medicine
- Radiology
- Vascular Biology
Background:
- Atherothrombosis is a systemic arterial disease impacting major vessels like the aorta and carotid arteries.
- Unstable atheromatous plaques are primary causes of severe complications, including stroke and myocardial infarction.
- Understanding plaque characteristics is vital for managing disease progression and selecting effective treatments.
Purpose of the Study:
- To review noninvasive imaging techniques for assessing carotid atheromatous plaques.
- To highlight the role of plaque imaging in understanding atherothrombosis.
- To provide insights into morphological and functional plaque evaluation in clinical practice.
Main Methods:
- Review of current noninvasive imaging modalities used in clinical settings.
- Focus on techniques for morphological assessment of carotid plaques.
- Emphasis on methods for functional evaluation of atheromatous plaques.
Main Results:
- Noninvasive imaging offers valuable insights into carotid plaque morphology.
- Functional assessment via imaging aids in identifying plaque instability.
- Current techniques enable detailed evaluation of plaques in the clinical setting.
Conclusions:
- Noninvasive plaque imaging is essential for managing atherothrombosis.
- Morphological and functional assessment of carotid plaques guides therapeutic decisions.
- Advancements in imaging are critical for improving patient outcomes in atherothrombosis.
Abstract:
Atherothrombosis is a systemic disease of the arterial wall that affects the carotid, coronary, and peripheral vascular beds, and the aorta. This condition is associated with complications such as stroke, myocardial infarction, and peripheral vascular disease, which usually result from unstable atheromatous plaques. The study of atheromatous plaques can provide useful information about the natural history and progression of the disease, and aid in the selection of appropriate treatment. Plaque imaging can be crucial in achieving this goal. In this Review, we focus on the various noninvasive imaging techniques that are being used for morphological and functional assessment of carotid atheromatous plaques in the clinical setting.
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