Noninvasive imaging of atheromatous carotid plaques

Umar Sadat1, Zhi-Yong Li, Martin J Graves

  • 1Department of Radiology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sadat.umar@gmail.com

Insights

Atherothrombosis, a disease of the arterial wall, leads to serious complications like stroke. Noninvasive imaging of carotid atheromatous plaques is crucial for understanding disease progression and guiding treatment.

Area of Science:

  • Cardiovascular Medicine
  • Radiology
  • Vascular Biology

Background:

  • Atherothrombosis is a systemic arterial disease impacting major vessels like the aorta and carotid arteries.
  • Unstable atheromatous plaques are primary causes of severe complications, including stroke and myocardial infarction.
  • Understanding plaque characteristics is vital for managing disease progression and selecting effective treatments.

Purpose of the Study:

  • To review noninvasive imaging techniques for assessing carotid atheromatous plaques.
  • To highlight the role of plaque imaging in understanding atherothrombosis.
  • To provide insights into morphological and functional plaque evaluation in clinical practice.

Main Methods:

  • Review of current noninvasive imaging modalities used in clinical settings.
  • Focus on techniques for morphological assessment of carotid plaques.
  • Emphasis on methods for functional evaluation of atheromatous plaques.

Main Results:

  • Noninvasive imaging offers valuable insights into carotid plaque morphology.
  • Functional assessment via imaging aids in identifying plaque instability.
  • Current techniques enable detailed evaluation of plaques in the clinical setting.

Conclusions:

  • Noninvasive plaque imaging is essential for managing atherothrombosis.
  • Morphological and functional assessment of carotid plaques guides therapeutic decisions.
  • Advancements in imaging are critical for improving patient outcomes in atherothrombosis.

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...