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Related Concept Videos

Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care evaluation by...
Patient-centered Care01:13

Patient-centered Care

Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic illness...
Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:

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Related Experiment Video

Updated: Jun 25, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

From evidence to action: Understanding clinical practice guidelines.

Rudolf W Poolman1, Cees C P M Verheyen, Gino M Kerkhoffs

  • 1Department of Orthopedic Surgery, Onze Lieve Vrouwe Gasthuis,, Amsterdam, the Netherlands. ieboswg@gmail.com

Acta Orthopaedica
|February 24, 2009
PubMed
Summary

Evidence-based guidelines are crucial for orthopedic surgeons to transition from opinion-based to evidence-based practice. This manuscript explains guideline development and evaluation, emphasizing their role in supporting informed clinical decisions.

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Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

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Last Updated: Jun 25, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

Area of Science:

  • Orthopedic Surgery
  • Evidence-Based Medicine
  • Clinical Practice Guidelines

Background:

  • Orthopedic surgeons increasingly rely on clinical practice guidelines to inform patient care.
  • A shift from opinion-based to evidence-based practice necessitates understanding and critically appraising guidelines.
  • Varying quality appraisal systems within guidelines pose challenges for consistent application.

Purpose of the Study:

  • To define clinical practice guidelines and their sources.
  • To outline methods for critically evaluating the quality of guidelines.
  • To illustrate the steps involved in developing evidence-based guidelines.

Main Methods:

  • A survey assessed Dutch orthopedic surgeons' perceptions of evidence-based guideline development and use.
  • The manuscript provides a narrative review of guideline evaluation and development processes.
  • An example of guideline development steps is presented.

Main Results:

  • Evidence-based guidelines are perceived by orthopedic surgeons as a key method for improving practice.
  • Critical appraisal of guidelines is essential due to diverse evidence and recommendation grading systems.
  • Well-developed guidelines synthesize the best available evidence.

Conclusions:

  • High-quality guidelines are indispensable tools for surgeons to implement evidence-based practice.
  • Understanding guideline appraisal and development empowers surgeons to utilize them effectively.
  • Guidelines provide graded recommendations to support clinical decision-making in orthopedics.