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Updated: Jun 25, 2026
09:14
Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
Unruptured cerebral aneurysms presenting with ischemic events
Nancy McLaughlin1, Michel W Bojanowski
1Division of Neurosurgery, Department of Surgery, Centre hospitalier de l'Université de Montréal-Hôpital Notre-Dame, Montreal, QC, Canada.
Summary
Unruptured cerebral aneurysms causing ischemic events pose treatment risks. This study found a noteworthy risk of thromboembolic events after treating these aneurysms, impacting patient outcomes.
Area of Science:
- Neurology
- Neurosurgery
- Vascular Medicine
Background:
- Unruptured cerebral aneurysms can manifest with ischemic symptoms.
- Assessing clinical and radiological features is crucial for treatment planning.
Purpose of the Study:
- To evaluate the clinical and radiological characteristics of patients with unruptured cerebral aneurysms presenting with ischemic events.
- To assess the outcomes following treatment for these specific aneurysms.
Main Methods:
- Retrospective analysis of 463 patients with unruptured cerebral aneurysms treated between 2000 and 2006.
- Inclusion criteria: aneurysms presenting with ischemic events.
- Outcome assessment at 12 months using the modified Rankin scale.
Main Results:
- Eleven patients with ischemic events due to unruptured aneurysms were included.
- Six patients showed acute ischemic lesions in the symptomatic territory.
- Treatment outcomes varied: coiling had complications (unsuccessful attempt, residual neck, recurrence), and surgery led to thromboembolism in 3/6 patients, though 5/6 achieved complete exclusion. Nine of ten treated patients had favorable outcomes.
Conclusions:
- Aneurysms presenting with ischemic events are often small and anteriorly located.
- Treatment of these aneurysms carries a significant risk of thromboembolic events.
- The findings are important considering the potential natural history of these aneurysms regarding stroke and bleeding risk.
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