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Updated: Jun 25, 2026
05:59
Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
Total synthesis and absolute configuration of the bisanthraquinone antibiotic BE-43472B
K C Nicolaou1, Yee Hwee Lim, Jochen Becker
1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. kcn@scripps.edu
Angewandte Chemie (International Ed. in English)
|February 25, 2009
Abstract:
An-T-biotic: The first total synthesis of the T-shaped bisanthraquinone natural product BE-43472B was accomplished and its absolute configuration assigned. Key transformations in the pivotal cascade sequence include a Diels-Alder reaction, a hemiketal formation, and a nucleophilic aromatic ipso substitution.
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