Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 25, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Bifocal nummular headache: the first three cases.

M L Cuadrado1, B Valle, C Fernández-de-las-Peñas

  • 1Department of Neurology, Hospital Clínico San Carlos, Universidad Complutense, Madrid, Spain. luz.cuadrado@urjc.es

Cephalalgia : an International Journal of Headache
|February 25, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differences and similarities between COVID-19 related-headache and COVID-19 vaccine related-headache. A case-control study.

Revista de neurologia·2023
Same author

Cervical muscle parameters and allodynia in migraine and cervical pain-A controlled study.

European journal of pain (London, England)·2023
Same author

Calcitonin gene-related peptide in migraine: from pathophysiology to treatment.

Neurologia·2022
Same author

Pain extent is associated with Central Sensitization Inventory but not widespread pressure pain sensitivity or psychological variables in women with fibromyalgia.

Scandinavian journal of rheumatology·2022
Same author

Validation of the Spanish-language version of the Montreal Cognitive Assessment as a screening test for cognitive impairment in multiple sclerosis.

Neurologia·2021
Same author

Document of revision and updating of medication overuse headache (MOH).

Neurologia·2020
Same journal

Effectiveness and clinical predictors of rimegepant for acute vertigo in vestibular migraine: A real-world cohort study.

Cephalalgia : an international journal of headache·2026
Same journal

Efficacy of digital therapeutic sinCephalea for personalised nutrition versus control for migraine prevention: A 12-week open-label randomised clinical trial.

Cephalalgia : an international journal of headache·2026
Same journal

SafeTy and effectiveness of Atogepant accoRding to the IHS outcome categories: A multicentric, prospective observational study in real life (the 24-week STAR study).

Cephalalgia : an international journal of headache·2026
Same journal

Placebo or active comparator in chronic migraine trials: Balancing evidence and practicality.

Cephalalgia : an international journal of headache·2026
Same journal

Impaired bone status in high frequency episodic or chronic migraine women: A case-control study with blood and densitometric parameters.

Cephalalgia : an international journal of headache·2026
Same journal

Distribution of intranasal lidocaine and its effect on electrically-evoked calcium signals in mouse trigeminal ganglion neurons.

Cephalalgia : an international journal of headache·2026
See all related articles

Nummular headache (NH) can occur in two distinct areas, challenging its definition as a single focal pain. This bifocal presentation suggests NH may affect multiple head regions simultaneously.

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Nummular headache (NH) is characterized by focal head pain in a small, specific head surface area.
  • The clinical presentation and diagnostic criteria for NH are still evolving.

Observation:

  • Three patients presented with focal head pain localized to two separate cranial areas.
  • This observation deviates from the typical definition of NH as exclusively unilateral or localized to one spot.

Findings:

  • The cases suggest the existence of bifocal nummular headache.
  • This expands the known clinical spectrum of this primary headache disorder.

Implications:

  • The findings indicate that the underlying mechanisms of NH might involve multiple cranial areas concurrently in some individuals.

Related Experiment Videos

Last Updated: Jun 25, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

  • Further research is needed to understand the pathophysiology and diagnostic implications of bifocal NH.