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Related Concept Videos

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Asepsis01:28

Asepsis

The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...

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Related Experiment Video

Updated: Jun 25, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Sepsis in the neonate.

Sandra L Gardner1

  • 1gardnerslconsult@aol.com

Critical Care Nursing Clinics of North America
|February 25, 2009
PubMed
Summary

Critical care nurses play a vital role in identifying and reporting potential sepsis in newborns within the neonatal intensive care unit, advocating for prompt diagnosis and treatment.

Area of Science:

  • Neonatal Intensive Care Unit (NICU) care
  • Pediatric critical care nursing
  • Neonatal sepsis and infection management

Background:

  • Neonatal sepsis is a life-threatening condition in newborns requiring vigilant monitoring.
  • Nurses in the neonatal intensive care unit (NICU) are pivotal in early sepsis detection.
  • While not diagnosing sepsis, critical care nurses significantly influence patient outcomes.

Purpose of the Study:

  • To outline the essential role of critical care nurses in managing neonatal sepsis.
  • To emphasize the importance of early recognition and reporting of potential sepsis in neonates.
  • To provide a guide for understanding sepsis-related issues in the NICU.

Main Methods:

  • Review of nursing responsibilities in sepsis identification.

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A Controlled Mouse Model for Neonatal Polymicrobial Sepsis

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Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

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Last Updated: Jun 25, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
14:54

A Controlled Mouse Model for Neonatal Polymicrobial Sepsis

Published on: January 27, 2019

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
07:30

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

Published on: June 15, 2019

  • Discussion of critical thinking and clinical observation skills for nurses.
  • Emphasis on interprofessional communication and patient advocacy.

    • Main Results:

    • Nurses must maintain a high index of suspicion for infection risk.
    • Nurses are crucial in recognizing clinical signs of septic neonates.
    • Effective reporting and advocacy by nurses lead to timely interventions.

    Conclusions:

    • Critical care nurses are essential in the early management of neonatal sepsis.
    • Nurses' roles include suspicion, recognition, reporting, and advocacy for neonates.
    • This article serves as a resource for NICU nurses managing sepsis.