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Updated: Jun 25, 2026

A 3D Quantification Technique for Liver Fat Fraction Distribution Analysis Using Dixon Magnetic Resonance Imaging
Published on: October 20, 2023
Evaluation of diffuse liver steatosis by ultrasound, computed tomography, and magnetic resonance imaging: which
Aliya Qayyum1, Daryl M Chen, Richard S Breiman
1Department of Radiology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0628, USA. aliya.qayyum@radiology.ucsf.edu
Purpose:
To compare ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) determination of diffuse liver steatosis.
Materials And Methods:
Quantification of liver steatosis on ultrasound, CT, and MRI was correlated with histopathology in 67 patients.
Results:
Opposed-phase MRI demonstrated the highest correlation with steatosis (0.68 and 0.69, P<.01; intraclass correlation coefficient, 0.93). Spearman's correlation (and intraclass correlation) coefficients were lowest for ultrasound [0.54, 0.33 (0.40)] and enhanced CT [0.33, 0.39 (0.97)].
Conclusion:
Opposed-phase MRI demonstrated best overall performance for determining steatosis.
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