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Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
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Aortic size in acute type A dissection: implications for preventive ascending aortic replacement.

Landi M Parish1, Joseph H Gorman, Sophia Kahn

  • 1Department of Surgery, Gorman Cardiovascular Research Group, University of Pennsylvania, Philadelphia, PA 19036, USA.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|February 25, 2009
PubMed
Summary

Most acute type A aortic dissections occur with aortic diameters less than 5.5 cm, challenging current guidelines. New methods are needed to identify dissection risk, with consideration for earlier prophylactic aortic replacement.

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Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Disease

Background:

  • Current guidelines recommend elective ascending aortic replacement for proximal aorta diameters >5.5 cm to prevent acute type A aortic dissection.
  • Limited data exist on the specific aortic dimensions at multiple levels in patients who experience acute type A dissections.

Purpose of the Study:

  • To characterize the size distribution of the proximal aorta at various levels in patients with acute type A aortic dissection.
  • To evaluate the current guidelines for elective ascending aortic replacement based on aortic diameter.

Main Methods:

  • Utilized preoperative transesophageal echocardiography to measure aortic diameters at the annulus, sinus, sinotubular junction, and ascending aorta.
  • Analyzed data from 177 non-Marfan patients with tricuspid aortic valves presenting with acute type A dissection over a 10-year period.
  • Calculated predicted aortic diameters based on age, gender, and body size for comparison with actual measurements.

Main Results:

  • 62% of patients had maximum aortic diameters <5.5 cm at the time of dissection.
  • 42% had maximum diameters <5.0 cm, and over 20% had dimensions <4.5 cm.
  • In women, 12% of dissected aortas measured <4.0 cm.

Conclusions:

  • The majority of acute type A aortic dissections occur in aortas smaller than the 5.5 cm threshold for elective replacement.
  • Alternative methods beyond size measurement are necessary for identifying patients at risk of aortic dissection.
  • Consideration for prophylactic ascending aortic replacement at 4.5 cm, particularly in high-volume centers or patients undergoing other cardiac surgery, is warranted, alongside aggressive medical management for diameters >4 cm.