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Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Menopause, cognitive ageing and dementia: practice implications.

Victor W Henderson¹

¹Departments of Health Research and Policy (Epidemiology) and of Neurology and Neurological Sciences, Stanford University, 259 Campus Drive, Stanford, CA 94305-5405, USA. vhenderson@stanford.edu

Menopause International

|February 25, 2009

Summary

This summary is machine-generated.

Cognitive aging impacts episodic memory. While natural menopause doesn't cause memory loss, surgical menopause and hormone therapy timing require further study for Alzheimer's disease risk assessment.

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

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Published on: January 11, 2020

Area of Science:

Neurology
Gerontology
Endocrinology

Background:

Cognitive aging affects episodic memory, with impairment potentially indicating early Alzheimer's disease.
Natural menopause does not objectively impair memory, but effects of surgical menopause are less understood.
Estrogen therapy post-menopause may increase dementia risk and offers no memory benefits.

Purpose of the Study:

To investigate the relationship between hormone therapy use during the menopausal transition and early postmenopause and Alzheimer's disease risk.
To examine the impact of surgical menopause on memory.
To clarify the "critical window" hypothesis regarding hormone therapy and dementia risk.

Main Methods:

Review of observational studies on hormone use, menopausal transition, and Alzheimer's disease risk.
Analysis of cognitive function in relation to surgical menopause.
Evaluation of existing literature on estrogen therapy and dementia.

Main Results:

Observational studies suggest a protective effect of hormone use during the menopausal transition, but potential biases exist.
The impact of surgical menopause on memory requires further investigation.
Late postmenopausal estrogen therapy is associated with increased dementia risk and no memory improvement.

Conclusions:

The timing of hormone therapy initiation around menopause may influence Alzheimer's disease risk, warranting further research.
Clinical implications for managing menopausal symptoms and assessing dementia risk are discussed.
More research is needed to confirm findings and address potential biases in observational data.