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Updated: Jun 25, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
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Manual versus automatic bladder wall thickness measurements: a method comparison study.

Matthias Oelke1, Charalampos Mamoulakis, Dirk T Ubbink

  • 1Department of Urology and Urologic Oncology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. oelke.matthias@mh-hannover.de

World Journal of Urology
|February 25, 2009
PubMed
Summary
This summary is machine-generated.

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Conventional ultrasound offers more reliable bladder wall thickness (BWT) measurements than the BVM 6500 device. Conventional ultrasound provides greater accuracy and can measure thicker bladder walls, ensuring comprehensive assessment for patients with lower urinary tract symptoms.

Area of Science:

  • Urology
  • Medical Imaging
  • Diagnostic Technology

Background:

  • Bladder wall thickness (BWT) is a key parameter in assessing lower urinary tract conditions.
  • Accurate BWT measurement is crucial for diagnosis and treatment monitoring.
  • Evaluating new technologies for BWT assessment is essential for improving clinical practice.

Purpose of the Study:

  • To compare the repeatability and agreement of conventional ultrasound BWT measurements with those obtained by the automated BVM 6500 device.
  • To assess the diagnostic accuracy and limitations of the BVM 6500 device for BWT measurement.

Main Methods:

  • Prospective evaluation of 50 adult patients with lower urinary tract symptoms.
  • BWT measurements using conventional ultrasound and the BVM 6500 device during two cystometry sessions at 150 ml and 250 ml bladder filling.

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  • Repeatability and variation assessed using Bland and Altman methods.

    • Main Results:

    • Conventional ultrasound yielded 0% invalid measurements, while the BVM 6500 had 2.1–14% invalid measurements.
    • Measurement variation was smaller for conventional ultrasound, especially at 250 ml bladder filling.
    • The BVM 6500 device failed to accurately measure BWTs exceeding 4 mm.

    Conclusions:

    • Both conventional ultrasound and BVM 6500 provide repeatable BWT measurements that agree with each other.
    • Conventional ultrasound demonstrates superior performance with smaller measurement variance and ability to measure thicker bladder walls.
    • Conventional ultrasound is more reliable for BWT assessment in all patients, including those with BWTs above 4 mm.