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Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
Published on: February 8, 2022
[Cardiology]
Christan Roguelov1, Pierre Vogt, Patrick Yerly
1Service de cardiologie, CHUV, 1011 Lausanne. Christan.Roguelov@chuv.ch
Insights
This review covers drug-eluting stents, cardiac resynchronization therapy, and atrial fibrillation management in heart failure. It also discusses new stent-valve technology and cardiac screening for athletes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Heart Failure Management
Context:
- Review of recent clinical trials and technological advancements in cardiovascular medicine.
- Focus on evidence-based practices and emerging therapies for complex cardiac conditions.
Purpose:
- To synthesize key findings from landmark trials like SYNTAX, FAME, HF-ACTION, REVERSE, and AF-CHF.
- To highlight innovations in percutaneous valve implantation and discuss cardiac screening in athletes.
Summary:
- Examines drug-eluting stents, questioning the efficacy of physical training in heart failure, and assessing cardiac resynchronization benefits.
- Evaluates rate versus rhythm control in atrial fibrillation with heart failure and introduces new stent-valve technologies.
- Addresses the critical aspect of screening athletes for underlying cardiac diseases to prevent sudden cardiac events.
Impact:
- Provides clinicians with concise summaries of pivotal studies to inform treatment decisions.
- Offers insights into novel interventional techniques and the importance of proactive cardiac screening in specific populations.
- Contributes to the ongoing discourse on optimizing cardiovascular care through evidence-based review and technological awareness.
Abstract:
This article reviews: 1) some of the results of drug eluting stents (SYNTAX and FAME); 2) the questionnable benefit of physical training in heart failure patients (HF-ACTION); 3) the benefit on cardiac remodelling of cardiac resynchronisation in heart failure patients (REVERSE study) and 4) the role of rate over rhythm control in patients with atrial fibrillation and heart failure (AF-CHF study); this article also reports the encouraging evolution of new technology allowing percutaneous implantation of stents-valves. Finally, this article address the screening of athletes for cardiac diseases.
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