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Updated: Jun 25, 2026

Screening for Phytoestrogens using a Cell-based Estrogen Receptor β Reporter Assay
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[Study on the estrogenic effects of isoflavone]

Wenzhong Zhang1, Ning Li, Rong Li

  • 1Institute of Nutrition and Food Safety, Chinese Center for Disease Prevention and Control, Beijing 100050, China. zhangwz2002@sina.com.cn

Wei Sheng Yan Jiu = Journal of Hygiene Research
|February 26, 2009
PubMed
Summary

Isoflavone and genistein exhibit endocrine-disrupting effects in rats, with genistein being the primary active component. Both compounds demonstrated a dose-response relationship in inducing uterine weight increase and proliferation.

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