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Updated: Jun 25, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
Multifunctional coprocessed excipients for improved tabletting performance.
Sumit Saha1, Aliasgar F Shahiwala
1National Institute of Pharmaceutical Education and Research (NIPER)-Ahmedabad, C/o. B.V. Patel Pharmaceutical Education and Research Development Centre, S.G. Highway, Thaltej, Ahmedabad-380054, India.
Coprocessed excipients, mixtures of multiple components, enhance tablet manufacturing by improving flow and compression. These advanced materials reduce the number of excipients needed for direct compression tablets.
Area of Science:
- Pharmaceutical Technology
- Materials Science
Background:
- Increasing demand for excipients with superior flow and compression properties in advanced tablet manufacturing.
- Limitations of traditional single excipients in meeting modern pharmaceutical production needs.
Purpose of the Study:
- To review the advantages and applications of coprocessed excipients in tablet formulation.
- To discuss material characteristics, coprocessing methods, and available products for direct compression.
Main Methods:
- Review of scientific literature on coprocessing techniques and excipient development.
- Analysis of market-available coprocessed excipients for direct compression applications.
Main Results:
- Coprocessing combines multiple excipients at the subparticle level, yielding synergistic benefits.
- These excipients offer improved flowability and compressibility, simplifying tablet formulation.
- Reduced need for multiple individual excipients in tablet formulations.
Conclusions:
- Coprocessed excipients represent a significant advancement in pharmaceutical excipient technology.
- They provide a versatile solution for direct compression, enhancing manufacturing efficiency and tablet quality.
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