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Quantifying Subcellular Ubiquitin-proteasome Activity in the Rodent Brain
Published on: May 21, 2019
Changes in activity of neutral proteases in tissues of ground squirrels in the dynamics of hibernation
E Z Emirbekov1, P M Nurmagomedova, M M Abasova
1Department of Biochemistry, Daghestan State University, Makhachkala.
Bulletin of Experimental Biology and Medicine
|February 26, 2009
Abstract:
Total activities of neutral proteases in the cerebral, hepatic, and myocardial tissues of ground squirrel vary during hibernation: in autumn (before hibernation) activities of the enzymes in the brain and myocardium start increasing, while in the liver they do not change. A common feature for all tissues is minimum activity of active neutral proteases in the middle of hibernation month 1 bout, while the maximum activity is recorded before awakening.
