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Response shift: a brief overview and proposed research priorities
Ruth Barclay-Goddard1, Joshua D Epstein, Nancy E Mayo
1Department of Physical Therapy, School of Medical Rehabilitation, University of Manitoba, R106-771 McDermot Ave., Winnipeg, MB, R3E 0T6, Canada. barclayg@cc.umanitoba.ca
Summary
This overview reviews response shift research in patient-reported outcomes. Key priorities include standardizing terminology, determining clinical importance, and improving measurement methods for health-related quality of life (HRQL).
Area of Science:
- Health Services Research
- Psychometrics
- Patient-Reported Outcomes
Background:
- Response shift is a phenomenon that can confound the interpretation of patient-reported outcomes (PROs).
- Understanding response shift is crucial for accurately measuring changes in health-related quality of life (HRQL).
Purpose of the Study:
- To review current methodologies in response shift research within the context of PROs.
- To stimulate further research and development in this critical area.
Main Methods:
- A narrative overview of existing research on response shift.
- Identification of key research priorities through synthesis of the literature.
Main Results:
- Consensus on terminology and theoretical models is needed.
- The clinical importance of response shift requires determination.
- Optimal methods for measuring and adjusting for response shift as a confounder must be established.
- Methods for identifying response shift when it is the focus of clinical treatment need to be ascertained.
- Translation of response shift knowledge into real-world settings is essential.
Conclusions:
- Addressing these research priorities will enhance understanding of response shift.
- Improvements in current analytical methods and development of new ones are anticipated.
- The clinical significance and impact of response shift on HRQL measurement will be clarified.
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