Ultra Wide Field Fluorescein Angiography Guided Targeted Retinal Photocoagulation (TRP)

We report two cases in which ultra wide field fluorescein angiography was used to direct targeted retinal photocoagulation (TRP) to areas of retinal capillary non-perfusion in an attempt to cause regression of diabetic neovascularization. By providing up to a 200 degree field of view, accurate delineation of retinal capillary non-perfusion and precise application of photocoagulation was possible. The application of TRP successfully led to the regression of the retinal neovascularization in our patients. Complications of conventional panretinal photocoagulation (PRP) such as visual field loss and macular edema may have been avoided. When TRP is used in conjunction with ultra wide field fluorescein angiography, preservation of functional retina may be possible while minimizing the amount of laser treatment that is applied to the retina.