[Hemolytic autoimmune anemia and perinatal HIV infection. A case report and brief review]

María del Carmen Gorbea-Robles1, Alma Buenrostro-Quijano, Patricia Trujillo-Linares

  • 1Departamento de Pediatría, Hospital de Infectología, Centro Medico Nacional La Raza. gorbeau@prodigy.net.mx

Insights

Autoimmune hemolytic anemia is a rare complication in pediatric HIV infection. This case report details a four-month-old girl with HIV and this condition, offering diagnostic and treatment insights.

Area of Science:

  • Pediatric Hematology
  • Infectious Diseases
  • Immunology

Background:

  • Hematological disorders are common in HIV infection.
  • Autoimmune hemolytic anemia (AIHA) is an exceptionally rare complication in pediatric HIV.
  • Fewer than ten cases of AIHA in pediatric HIV have been documented globally.

Observation:

  • A four-month-old infant with perinatally acquired human immunodeficiency virus (HIV) infection presented with AIHA.
  • The infant's clinical presentation and diagnostic workup are detailed.

Findings:

  • The case highlights the association between pediatric HIV and AIHA.
  • Diagnostic challenges and initial treatment strategies for this rare condition were encountered.

Implications:

  • This report contributes to the limited literature on AIHA in pediatric HIV.
  • It proposes a critical pathway for the diagnosis and initial management of this rare complication.
  • Understanding this association is crucial for pediatricians managing HIV-infected children.

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