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[Hemolytic autoimmune anemia and perinatal HIV infection. A case report and brief review]
María del Carmen Gorbea-Robles1, Alma Buenrostro-Quijano, Patricia Trujillo-Linares
1Departamento de Pediatría, Hospital de Infectología, Centro Medico Nacional La Raza. gorbeau@prodigy.net.mx
Insights
Autoimmune hemolytic anemia is a rare complication in pediatric HIV infection. This case report details a four-month-old girl with HIV and this condition, offering diagnostic and treatment insights.
Area of Science:
- Pediatric Hematology
- Infectious Diseases
- Immunology
Background:
- Hematological disorders are common in HIV infection.
- Autoimmune hemolytic anemia (AIHA) is an exceptionally rare complication in pediatric HIV.
- Fewer than ten cases of AIHA in pediatric HIV have been documented globally.
Observation:
- A four-month-old infant with perinatally acquired human immunodeficiency virus (HIV) infection presented with AIHA.
- The infant's clinical presentation and diagnostic workup are detailed.
Findings:
- The case highlights the association between pediatric HIV and AIHA.
- Diagnostic challenges and initial treatment strategies for this rare condition were encountered.
Implications:
- This report contributes to the limited literature on AIHA in pediatric HIV.
- It proposes a critical pathway for the diagnosis and initial management of this rare complication.
- Understanding this association is crucial for pediatricians managing HIV-infected children.
Abstract:
The hematological disorders are frequent in HIV infection; however the hemolytic anemia is a rare complication in pediatric patients. At this moment exist less than ten cases reported in medical literature. The authors reported a four month old girl with perinatal docu-mented infection by HIV associated to autoimmune hemolytic anemia, and they propose a critic route for diagnosis and initial treatment.
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