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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

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Updated: Jun 25, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

Maternal mortality: an autopsy audit.

K D Jashnani1, A B Rupani, R J Wani

  • 1Department of Pathology, T N Medical College and B Y L Nair Ch Hospital, Mumbai Central, Mumbai-400 008, India. kusumjash@hotmail.com

Journal of Postgraduate Medicine
|February 27, 2009
PubMed
Summary
This summary is machine-generated.

This study audited maternal autopsies, revealing a high maternal mortality ratio (MMR) and identifying key causes of death. The audit highlighted areas for improving autopsy practices to better understand pregnancy-related pathophysiology.

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Area of Science:

  • Obstetrics and Gynecology
  • Pathology
  • Public Health

Background:

  • Maternal autopsies are crucial for understanding mortality but require standardized protocols.
  • Auditing these autopsies can identify systemic issues and improve diagnostic accuracy.

Purpose of the Study:

  • To calculate the maternal mortality ratio (MMR) at a tertiary care hospital.
  • To correlate clinical diagnoses with autopsy findings and audit current autopsy practices.
  • To identify deficiencies in maternal autopsy procedures and suggest improvements.

Main Methods:

  • A retrospective review of 89 maternal death autopsies conducted between 2003 and 2007.
  • Detailed analysis of autopsy findings alongside available clinical information.

Main Results:

  • A high maternal mortality rate of 1133 per 100,000 live births was observed.
  • Acute fulminant viral hepatitis was the leading indirect cause of death (41.5%).
  • Direct causes included pregnancy-induced hypertension (13.4%) and puerperal sepsis (11.2%).

Conclusions:

  • Maternal mortality autopsies require enhanced clinicopathologic correlation and microbiological studies.
  • Challenges were noted in identifying the placental bed postpartum.
  • A systematic approach to maternal autopsies is essential for understanding pregnancy-related disease pathophysiology.