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Updated: Jun 25, 2026

Tropomodulin 3 Overexpression as a Marker for Platinum Resistance and Immune Infiltration in Ovarian Cancer
Published on: August 2, 2024
Cisplatinum and docetaxel for ovarian cancer in pregnancy
Abdulrahim A Rouzi1, Nora N Sahly, Naif F Sahly
1Department of Obstetrics and Gynecology, King Abdulaziz University, PO Box 80215, Jeddah 21589, Saudi Arabia. aarouzi@gmail.com
Background:
There is limited data on chemotherapy for advanced ovarian cancer during pregnancy. Most women received cisplatin-based chemotherapy. There are no published reports on the use of docetaxel for ovarian cancer in pregnancy.
Case:
A 32-year-old pregnant lady underwent laparatomy at 18-week gestation for ruptured ovarian cyst. The pregnancy was the result of in vitro fertilization with intracytoplasmic sperm injection. Left salpingo-oophorectomy and omental biopsy were done. A diagnosis of stage IIIC, poorly differentiated papillary serous adenocarcinoma of the ovary was made. She was given four cycles of cisplatinum and docetaxel followed by cesarean hysterectomy, right salpingo-oophorectomy, and cytoreductive surgery. The mother is well and has completed six cycle of chemotherapy.
Conclusion:
This is the first report on the use of docetaxel during pregnancy for ovarian cancer.
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