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Updated: Jun 25, 2026

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
Published on: August 9, 2024
Phase-contrast magnetic resonance quantification of normal pulmonary venous return
Hyun Woo Goo1, Abdulmajeed Al-Otay, Lars Grosse-Wortmann
1Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Purpose:
To assess the feasibility of phase-contrast magnetic resonance (PCMR) in quantifying the pulmonary venous return in normal subjects.
Materials And Methods:
PCMR was performed in 12 healthy adult volunteers (mean age 38 years, range 27-60 years; 9 men; body surface area 1.81+/-0.15 m2) for the ascending and descending aorta, caval veins, main and branch pulmonary arteries, and pulmonary veins. Two readers independently quantified blood flow in all subjects.
Results:
Intraobserver differences were -2.0% (95% confidence interval [CI]: -9.9% to 5.9%), -4.5% (95% CI: -15.6% to 6.5%), and -0.7% (95% CI: -4.5% to 3.0%) for all vessels, pulmonary veins, and other great vessels, respectively. Interobserver differences were -2.0% (95% CI: -10.6% to 6.6%), -3.1% (95% CI: -16.0% to 9.9%), and -1.4% (95% CI: -6.4% to 3.5%) for all vessels, pulmonary veins, and other great vessels, respectively. Pulmonary venous flow volume showed high correlations with the volumes of the pulmonary arterial flow, systemic arterial flow, and systemic venous flow (r=0.76-0.92, P<0.005).
Conclusion:
Flow quantification of normal pulmonary venous return using PCMR is feasible with high reproducibility and accuracy.
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