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Updated: Jun 25, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
Intramedullary osteosynthesis for fracture associated with osteogenesis imperfecta
H Wolf1, K Sarahrudi, V Vécsei
1Department of Trauma Surgery, Medical University Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Harald.Wolf@meduniwien.ac.at
Abstract:
Our aim was to analyse the complications associated with intramedullary stabilisation of the bone fractures which are a common complication of osteogenesis imperfecta. A total of 12 fractures among six individuals with osteogenesis imperfecta were treated by intramedullary stabilisation. The mean age of the patients (three male and three female) was 19.4 years, range 7-42 years. The most common fracture site was the femoral midshaft (seven fractures). After implant removal, one new fracture and one re-fracture occurred. Operative stabilisation of fractures is a safe treatment option for osteogenesis imperfecta.
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