Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

Probiotics

Probiotics

Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...

Dysbiosis of the Gut Microbiota

Dysbiosis of the Gut Microbiota

The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...

Chronic Bowel Disorders: Introduction

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...

Inflammatory Bowel Disease V: Surgical Management

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Colorectal sessile serrated lesion with large size or synchronous neoplasm: a prospective study.

European journal of gastroenterology & hepatology·2019

Same author

Decompensated cirrhotics have slower intestinal transit times as compared with compensated cirrhotics and healthy controls.

Journal of clinical gastroenterology·2013

Same author

New strategies for the management of diverticular disease: insights for the clinician.

Therapeutic advances in gastroenterology·2013

Same author

24 Versus 48-hour bravo pH monitoring.

Journal of clinical gastroenterology·2011

Same author

Features and management of colonic diverticular disease.

Current gastroenterology reports·2010

Same author

Education of gastroenterology trainees: first annual fellows' nutrition course.

Journal of clinical gastroenterology·2008

Search research articles

Related Experiment Video

Updated: Jun 25, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Probiotics and diverticular disease.

Anish Sheth¹, Martin Floch

¹Yale University School of Medicine, Section of Digestive Diseases, 40 Temple St, New Haven, CT 06510, USA. anish.sheth@yale.edu

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition

|February 27, 2009

Summary

This summary is machine-generated.

Diverticular disease management may benefit from probiotics. This review explores the role of probiotics in addressing inflammation and symptoms associated with diverticular disease.

More Related Videos

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Published on: July 27, 2022

Related Experiment Videos

Last Updated: Jun 25, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation

Published on: July 27, 2022

Area of Science:

Gastroenterology
Microbiology
Nutritional Science

Background:

Diverticular disease is highly prevalent in Western countries.
Inflammatory complications, including acute pain and fever, are common manifestations.
Chronic symptoms can mimic irritable bowel syndrome or inflammatory bowel disease.

Purpose of the Study:

To discuss the rationale for using probiotics in diverticular disease.
To review current clinical data on probiotic efficacy for diverticular disease management.

Main Methods:

Literature review of existing clinical data.
Discussion of the pathogenesis of diverticular inflammation, focusing on bacterial flora.

Main Results:

The review synthesizes available evidence on probiotics for diverticular disease.
Identifies the potential role of altered peridiverticular bacterial flora in disease pathogenesis.

Conclusions:

Probiotics show potential as an adjunct therapy for managing diverticular disease.
Further research is warranted to establish definitive clinical guidelines for probiotic use.