Massive infantile nephroblastomatosis: a clinical, radiological, and pathological analysis of four cases

Four cases of massive infantile nephroblastomatosis with up to three and one-half years follow-up are described. Great similarity was found clinically, radiologically and pathologically, which distinguishes this entity from true Wilms' tumor. The course of the renal lesion following treatment was monitored by sequential radiological and biopsy studies. The pathogenesis, natural history, and management are discussed.