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Related Experiment Video

Updated: Jun 25, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Aspheric intraocular lens selection based on corneal wavefront.

Mark Packer¹, I Howard Fine, Richard S Hoffman

¹Oregon Eye Institute, Eugene, Ore., USA. mpacker@finemd.com

Journal of Refractive Surgery (Thorofare, N.J. : 1995)

|February 28, 2009

Summary

Selecting aspheric intraocular lenses (IOLs) based on preoperative corneal aberration is feasible. This customized approach to cataract surgery effectively targets zero postoperative spherical aberration, improving visual outcomes.

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$Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter$

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Published on: September 16, 2025

Area of Science:

Ophthalmology
Optics
Biomedical Engineering

Background:

Spherical aberration can negatively impact visual quality after cataract surgery.
Aspheric intraocular lenses (IOLs) are designed to reduce spherical aberration.
Personalized IOL selection may optimize refractive outcomes.

Purpose of the Study:

To assess the feasibility of targeting zero total postoperative spherical aberration.
To evaluate the effectiveness of selecting aspheric IOLs based on preoperative corneal spherical aberration.

Main Methods:

Candidates for cataract surgery selected aspheric IOLs based on corneal spherical aberration measurements.
The target was zero total postoperative wavefront spherical aberration (Z4,0).
Corneal topographic spherical aberration (Z4,0) was measured, and IOLs were chosen to minimize the sum of corneal and pseudophakic spherical aberration.

Main Results:

Thirty eyes from 18 patients were analyzed.
Total postoperative ocular spherical aberration was -0.013+/-0.072 microm.
Mean absolute predictive error was 0.058+/-0.056 microm, indicating accurate IOL selection.

Conclusions:

Customized selection of aspheric IOLs based on corneal wavefront is feasible.
This method yields favorable results compared to studies with unselected patient populations.
Personalized IOL selection offers a promising approach for optimizing visual outcomes in cataract surgery.