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Related Experiment Video

Updated: Jun 25, 2026

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration

Published on: July 8, 2021

Histomorphologic study of discoid meniscus.

Anestis Papadopoulos¹, John M Kirkos, George A Kapetanos

¹Third Orthopaedic Department, Aristotle University of Thessaloniki, Papageorgiou General Hospital, Thessaloniki, Greece. altairpap@yahoo.com

Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association

|February 28, 2009

Summary

The discoid meniscus shows disorganized circular collagen fibers compared to normal menisci, indicating a structural defect. This disorganization may explain higher tear rates in discoid menisci.

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Area of Science:

Orthopedic Surgery
Biomedical Engineering
Histopathology

Background:

The menisci are crucial for knee joint function, providing shock absorption and stability.
Discoid menisci are a congenital anomaly with altered morphology, often associated with knee pain and tears.

Purpose of the Study:

To compare the matrix collagen network integrity in discoid lateral menisci versus normal lateral menisci.
To determine if discoid menisci represent a structural abnormality or a morphological variant.

Main Methods:

Histomorphological examination of arthroscopically excised discoid lateral menisci (n=10).
Comparison with intact lateral menisci from knee arthroplasty controls.
Assessment of radial and circular collagen fiber systems integrity.

Main Results:

Statistically significant disorganization of the circular collagen network in discoid menisci compared to normal menisci (P < .001).
Heterogeneous arrangement of circumferentially arranged collagen fibers observed in discoid menisci, particularly in the posterior third.
Evidence of discontinuity and inhomogeneity in the circumferential collagen network.

Conclusions:

Discoid meniscus exhibits a structural lesion characterized by collagen network disorganization, not merely a morphological variant.
The compromised circular collagen system in discoid menisci may contribute to their higher susceptibility to tears and degeneration.