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Uniparental disomy in cancer

Musaffe Tuna1, Sakari Knuutila, Gordon B Mills

  • 1Department of Cancer Genetics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. mtuna9@gmail.com

Trends in Molecular Medicine
|February 28, 2009
PubMed
Summary

Uniparental disomy (UPD), where both chromosome copies come from one parent, can cause developmental diseases or cancer. This review explores UPD mechanisms and their link to cancer development.

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