Related Experiment Video
Updated: Jun 25, 2026

Clinical Microfluidic Chip Platform for the Isolation of Versatile Circulating Tumor Cells
Published on: October 13, 2023
The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients
Lecia V Sequist1, Sunitha Nagrath, Mehmet Toner
1Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA. lvsequist@partners.org
Abstract:
Circulating tumor cells (CTCs) are rare cells that originate from a malignancy and circulate freely in the peripheral blood. The ability to capture and study CTCs is an emerging field with implications for early detection, diagnosis, determining prognosis and monitoring of cancer, as well as for understanding the fundamental biology of the process of metastasis. Here, we review the development and initial clinical studies with a novel microfluidic platform for isolating these cells, the CTC-chip, and discuss its potential uses in the study of lung cancer.

