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Meningioangiomatosis associated with meningioma: a case report

Ali Saad1, Rebecca Folkerth, Tina Poussaint

  • 1Department of Pathology, Children's Hospital, Boston, Massachusetts 02115, USA. ali.saad@childrens.harvard.edu

Acta Cytologica
|March 3, 2009
PubMed
Abstract

Insights

Meningioangiomatosis rarely occurs with meningioma, presenting diagnostic challenges. This case highlights unique cytologic features for accurate intraoperative diagnosis of this rare brain tumor variant.

Area of Science:

  • Neuropathology
  • Neurosurgery
  • Cytopathology

Background:

  • Meningioangiomatosis is a rare meningovascular disorder.
  • It infrequently co-occurs with meningioma.
  • Imaging may not distinguish it from malignant processes due to cortical infiltration.

Observation:

  • A 3-year-old girl presented with refractory seizures.
  • Neuroimaging revealed an ill-defined left frontal lobe abnormality.
  • Intraoperative smears showed coexisting meningioangiomatosis and meningioma.

Findings:

  • This case details the cytologic features of meningioangiomatosis and meningioma.
  • It emphasizes diagnostic pitfalls in differentiating benign from malignant-appearing lesions.
  • This is the first description of cytologic features on smear preparation for this combined entity.

Implications:

  • Familiarity with these cytologic features is crucial for accurate intraoperative consultation.
  • Improved recognition aids in appropriate surgical management of this rare condition.
  • Understanding these features can prevent misdiagnosis as a high-grade tumor.

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