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[Bioluminescent reporter genes]

Simon T M Allard1

  • 1Promega Corporation.

Postepy Biochemii
|March 3, 2009
PubMed

Abstract:

Reporter genes typically are used to monitor changes in transcriptional rate, which can vary quickly in response to a specific cellular event. Here we give background on bioluminescent reporters and assays and their uses in research.

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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...

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