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Related Concept Videos

Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...

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Bioluminescent Bacterial Imaging In Vivo
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[Bioluminescent reporter genes].

Simon T M Allard1

  • 1Promega Corporation.

Postepy Biochemii
|March 3, 2009
PubMed
Summary
This summary is machine-generated.

Reporter genes track transcriptional changes in cells. Bioluminescent reporters and assays offer a sensitive method for monitoring these dynamic cellular events in research.

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Area of Science:

  • Molecular Biology
  • Biochemistry

Context:

  • Reporter genes are essential tools in molecular biology.
  • Monitoring transcriptional rate is crucial for understanding cellular responses.

Purpose:

  • To provide background on bioluminescent reporters and assays.
  • To explain their applications in scientific research.

Summary:

  • Reporter genes enable the observation of rapid changes in gene expression.
  • Bioluminescent systems offer a sensitive detection method for these changes.

Impact:

  • Facilitates the study of dynamic cellular processes.
  • Enhances the understanding of gene regulation and cellular signaling.