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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...

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Medially originated inverted papilloma.

Ta-Jen Lee1, Chi-Che Huang, Yi-Wei Chen

  • 1Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital, Chang Gung University, Kwei-Shan, Taoyuan, Taiwan.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|March 3, 2009
PubMed
Summary

Medially originated inverted papilloma (MOIP) can behave aggressively, but origin-based categorization aids surgical planning. Radical procedures were reserved for advanced laterally originated inverted papilloma (LOIP), with similar recurrence rates for both types.

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Pathology

Background:

  • Inverted papilloma (IP) is a benign neoplasm of the sinonasal tract.
  • Tumor origin influences IP behavior and treatment strategies.

Purpose of the Study:

  • To characterize medially originated inverted papilloma (MOIP) and compare it with laterally originated inverted papilloma (LOIP).
  • To evaluate the clinical behavior and treatment outcomes based on IP origin.

Main Methods:

  • Retrospective chart review of 83 sinonasal inverted papilloma (IP) patients.
  • Categorization of tumors as MOIP (nasal septum/turbinates) or LOIP (sinuses).

Main Results:

  • MOIP (34%) and LOIP (66%) were identified.
  • MOIP from the middle turbinate showed more aggressive behavior than ethmoid LOIP (P=0.009) but less than maxillary medial wall LOIP (P<0.05).
  • Radical procedures were used for LOIP (14 cases) but not MOIP (P=0.002); recurrence rates were similar (P=0.472).

Conclusions:

  • Categorizing IP by tumor origin improves surgical design and tumor excision.
  • While MOIP can be aggressive, radical surgery was only needed for advanced LOIP, without impacting recurrence rates.